WebNational Center for Biotechnology Information WebNov 14, 2024 · Cefepime is a widely used antibiotic with neurotoxicity attributed to its ability to cross the blood–brain barrier and exhibit concentration-dependent ϒ-aminobutyric …
The Safety of Treatment with Cefepime in Elderly Patients
WebNov 21, 2024 · The most common EEG abnormalities described in cefepime induced neurotoxicity (CIN) are triphasic waves, focal sharp waves and periodic discharges, however those abnormalities are non specific. The objectives of this study are: a) to compare the EEG findings in patients with cefepime trough levels >25 with and without documented … WebAug 7, 2024 · EEG may be insightful in providing evidence of encephalopathy via the presence of triphasic waves or NCSE evident by ≤ 2.5 Hz epileptiform discharges. 13 Obtaining lab values for cefepime serum concentration may also be useful in exploring cefepime-induced neurotoxicity, though this lab order is not widely practiced. trouser socks comfort toe
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WebJul 3, 2024 · Alternative therapy: Cefepime, meropenem. Cephalosporin-resistant (MIC ≧1-2 ug/mL) (27062 097, 31021955) ... EEG (continuous EEG is the most sensitive for detection of non-convulsive seizures, but if … WebApr 10, 2024 · Electroencephalogram, voltage topography and magnetic resonance imaging findings. a An electroencephalogram (EEG) on Day 5 showing repeated low-voltage ictal discharges from the right occipital region (red line). Note that the sensitivity of EEG recording is displayed at approximately three-times higher than the ordinary sensitivity … WebAdditionally, EEG spikes were recorded for mice that were given cefepime (500 mg/kg). In corneal kindled mice following cefepime injection, mean seizure stage was significantly higher than that following meropenem injection. The convulsive liability of cefepime is significantly higher than that of meropenem in normal and corneal kindled mice. trouser socks with backless loafers