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Danish 82c trial

WebMay 15, 1999 · Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c … WebAug 28, 2016 · Principal Findings: The primary outcome, incidence of all-cause mortality, occurred in 21.6% of the ICD group versus 23.4% of the control group (p = 0.28). Younger patients (<59 years) appeared to derive greater benefit from ICD implantation versus older patients (p for interaction = 0.009). Sudden cardiac death: 4.3% versus 8.2%; …

Postoperative radiotherapy in high-risk postmenopausal breast …

WebBetween 1982 and 1990, postmenopausal women with high-risk breast cancer (stage II or III) were randomly assigned adjuvant tamoxifen (30 mg daily for 1 year) alone (689) or … WebNov 24, 2010 · The Danish 82c trial randomized 1375 postmenopausal high-risk breast cancer patients younger than 70 years of age, status post total mastectomy and axillary dissection, to radiation therapy plus tamoxifen vs. tamoxifen alone . impd officers https://northeastrentals.net

Postoperative radiotherapy in high-risk postmenopausal

Webmastectomy and axillary node sampling (13). The Danish 82c trial randomized 1,375 high-risk postmenopausal women who underwent total mastectomy with partial axillary node dissection to tamoxifen alone or tamoxifen with PMRT (14). Radiation in both these trials was delivered to the chest wall and WebIn Postmenopausal Danish Trial 82c, as in Premenopausal Danish Trial 82b, inadequate surgical Tx of the axilla resulted in a median of only 7 axillary LNs removed at surgery. A suboptimal duration of tamoxifen was also employed (1 yr vs. the typical 5 yrs). WebTrial Oversight. The Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) was an investigator-initiated multicenter, randomized ... impd org

Postmastectomy radiation therapy in locally advanced breast …

Category:Defibrillator Implantation in Patients with Nonischemic …

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Danish 82c trial

Defibrillator Implantation in Patients with Nonischemic Systolic Heart

WebThe Danish 82c trial randomized 1,375 high-risk postmenopausal women who underwent total mastectomy with partial axillary node dissection to tamoxifen alone or tamoxifen …

Danish 82c trial

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WebNov 15, 2001 · By comparison, in the Danish 82c trial, 33% of patients had ≥4 nodes involved (2). For postmastectomy patients treated on randomized trials who received chemotherapy without radiotherapy, the LRF rates for patients with 1–3 and ≥4 lymph nodes were 6–33% and 14–46%, respectively (34). WebStudy with Quizlet and memorize flashcards containing terms like Lifetime Risk of breast cancer, EIC definition, NSABP B-04 arms and more.

WebDec 3, 2024 · Ultimately, the DANISH trial suggests that routine ICD therapy for all patients with symptomatic ischemic cardiomyopathy with ≤35% may not result in the strong … WebAug 1, 2006 · (1999) Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 353: 1641–1648

WebMay 8, 2014 · The Danish 82b trial demonstrated the use of PMRT, in conjunction with systemic chemotherapy, reduced local failure (LF) by 23 % and improved diseasefree survival (DFS) and OS by 14 % and 9 %, respectively. 7 In the Danish 82c trial the use of PMRT, in addition to hormonal therapy, reduced LF by 27 % and improved OS by 9 %.8 … WebJul 2, 2024 · In this trial, 318 premenopausal women with high-risk breast cancer were randomized to mastectomy and chemotherapy or chemotherapy plus RT. Patients in the radiation arm exhibited a reduction in 10-year LRR, as in the DBCCG trials. The Danish 82c trial studied the effect of PMRT in high-risk postmenopausal women using a similar …

WebOct 2, 1997 · Background: Irradiation after mastectomy can reduce locoregional recurrences in women with breast cancer, but whether it prolongs survival remains controversial. We …

WebMay 15, 1999 · Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Author links open overlay panel Dr Marie Overgaard MD a, Maj-Britt Jensen MSc c, Jens Overgaard MD b, Per S Hansen MD f, ... list words that are exclamatoryWebJun 11, 2024 · An increase in the actuarial risk of ischemic heart disease was not seen in the analysis of the Danish Breast Cancer Group trials 82b and 82c, in which more than 3,000 patients were followed (5) . These data have led Kurtz to note the potential hazard of thoracic irradiation and to highlight the importance of radiotherapy technique in breast ... impd online reportingWebApr 1, 2010 · In a subsequent analysis of the 82b and 82c trials no increase in cardiac morbidity was seen in the irradiated arm. 14 The Danish 82b trial was criticised for the suboptimal intensity of chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil (CMF) 15 and inadequate axillary surgery with only a median of 7 nodes … impd officer rosterWebJan 12, 2024 · NSABP-B06 (1976–1980) 25-Year follow-up of a randomized trial of 590, 632, and 629 patients treated with mastectomy, lumpectomy alone, or lumpectomy followed by adjuvant RT Cumulative incidence of … impd officer shotWebNov 1, 2001 · On the heels of those influential papers, Dr. Marie Overgaard et al. has published another Danish trial regarding the benefits of RT on survival in high risk … impdp access_methodWebOct 15, 2024 · The role of RNI has primarily been defined by studies that delivered adjuvant chemotherapy including the original postmastectomy randomized trials (except Danish … impdp bufferWebDec 5, 2024 · Apart from menopausal status, the DBCG 77B and 82C trials had identical selection criteria, but while 77B trial used classic CMF with oral cyclophosphamide a … impd org.br